Faculty of Sciences

Bachelor of Science in Biochemistry

Hybrid & English

Mission

The mission of the undergraduate biochemistry program is to develop students' knowledge in the modern foundations underlying biochemistry, cell biology, genetics, microbiology, and chemistry. The program will foster a culture that values our students, strives to help them become self­learners and promotes an understanding that social consciousness and ethical behavior are essential features of a principled biochemistry community. The program will train students for graduate programs in science or as professionals in a variety of school, government or private laboratory positions.

Program Educational Objectives

1. Graduates will work as members of multidisciplinary teams (pharmaceutical, biology and chemistry) and develop and practice written and oral communication skills, both within the team and for a broader audience.
2. Graduates will have the ability to solve theoretical and open­ended biochemical problems with opportunities to design and conduct biochemical experiments to meet specific needs and constraints.
3. Graduates will recognize the importance of continued self­improvement, to engage in lifelong learning, and to advance the well­being of our community through an understanding of the social, ethical and cultural context of their work.

Program Outcomes

a. Students will bring together the modern foundational knowledge underlying biochemistry, cell biology, genetics, microbiology, and chemistry.
b. Extrapolate the understanding of the relationships between chemistry and biological sciences.
c. Explain, model and conceptualize chemical and life processes at the molecular level.
d. Manipulate, synthesize, and analyze molecules and their properties using contemporary laboratory equipment, methods and computer software.
e. Practice safe handling of equipment, molecules, and organisms.
f. Apply concepts of approximation, estimation, precision, and accuracy in biochemistry data acquisition.
g. Communicate the results of their work to chemists, biologists or to a lay audience.
h. Recognize the need for and have the ability to engage in lifelong learning.
i. Find employment in a health laboratory, in industry or in government, or be accepted into graduate studies or find employment in school systems.
j. Develop an awareness of ethical, professional and social issues and responsibilities.
96 credits
General Education - Hybrid
Arts and Humanities
6 credits
Behavioral and Social Sciences
3 credits
Civic Engagement
2 credits
English & French Communication
6 credits
MAT216General Mathematics
3 credits
This course provides the basics needed by students to progress in their specialty courses. Topics covered include: function of a real variable, elementary functions, Taylor's expansion, simple integral and methods of integration, differential equations, multivariable functions, continuity, partial derivative, the chain rule, differential, introduction to double integrals, methods of integration, Matrix calculus, determinants, and linear systems.
PSC210General Physics
3 credits
The objective of this course is the introduction of various laws, principles and physical mechanisms, whose understanding is essential to students pursuing studies in various branches of science. This course consists of several independent parts. The first one deals with dynamics, the different types of motion, Newton's laws, and conservation of energy. The second part deals with hydrostatics and fluid dynamics. The third part deals with thermodynamics, calorimeters, the first principle and the basic transformations, the ideal gas, and thermodynamic cycles. The fourth part concerns the analysis of simple electrical circuits using Kirchhoff laws and the movement of a particle in an electromagnetic field. In the fifth part we talk about relativity, the theory of photons, and the photoelectric effect. Upon completion of this course the students will have acquired sufficient knowledge of several basic principles in physics and be familiar with these various topics.
History of Lebanon
3 credits
STS220Probability and Applied Statistics
3 credits    |    Pre-requisite: MAT213 Or MAT215 Or MAT216 Or MAT218 Or NUT210 Or NTR210
This course prepares students for the practical use of probability and statistics in the biomedical field (agronomy, chemistry, biochemistry, nutrition, medicine, etc.). Topics covered are: elements of descriptive statistics, population, statistical unit, frequency distribution characteristic of central tendency and dispersion; concepts of probability and combinatorics, conditional probability and Bayes' formula, applications, discrete and continuous random variables, expectation and moments, weak law of large numbers, empirical frequencies and probabilities customary laws (Binomial, Multinomial, Poisson, Normal) and asymptotic behavior, the law of large numbers, sampling and estimation, introduction to the use of hypothesis tests, and the Chi­2 contingency table.
Religious Sciences
3 credits
Sports
1 credits
Common Core - Hybrid
CHM222Chemistry of Solutions
3 credits    |    Pre-requisite: CHM212
This course brings together the necessary knowledge to understand the reactions in solutions that are the fundamentals of many methods used both in the fields of chemistry, biochemistry or biology, as well as in pharmaceutical analysis. After a reminder of key points and generalities, the course develops four main components: acid­base equilibria, complexation equilibria, redox reactions and the formation reactions of poorly soluble compounds.
BIO201General biology I
3 credits
BIO202General biology II
3 credits
CHE212General Chemistry
3 credits
The purpose of this course is to present a general outline on chemistry. Through this course chemistry is introduced in its various aspects: the structure of the atom, the various models, and the properties of the elements in the periodic table; various chemical bonds, the Lewis structure, VSEPR rules; thermochemistry, thermodynamics and chemical equilibrium; kinetic chemistry, reactions rate orders, the Arrhenius law; solutions chemistry, acids and bases and various acid­base equilibrium; complexation, liquid solid equilibrium and solubility product; and redox titration and electrochemical cells.
BLG322Genetics
3 credits    |    Pre-requisite: BIO211 Or BIO210 Or BLG211
The purpose of this course is to provide basic knowledge of genetics: cytogenetic (the study of chromosomes), formal genetics (the study of hereditary transmission mechanisms), molecular genetics (the study of nucleic acids, their replication, transcription and translation), and bacterial genetics.
BIO321Human Anatomy and Physiology
3 credits
CHE471Lab of Chromatography and Spectroscopy
1 credits    |    Pre-requisite: CHM370
This laboratory aims to introduce students to the different experimental techniques of quantification and characterization: the separation process and spectroscopic evaluation. All techniques deal with multidisciplinary skills for those with an interest in industrial chemistry, biochemistry and SVT.
CHM370Laboratory of Analytical Chemistry
1 credits    |    Pre-requisite: CHM222 And CHM270
The purpose of this lab is to give students the opportunity to practice the knowledge they have learned in class. They will use the following techniques: titration of a polyacid, preparation and properties of buffer solutions, titration by indirect redox, complexometric assay, conductometric titration, study of solubility, color indicators, and determination of an equilibrium constant by the method of partition coefficients.
BCH470Laboratory of Biochemistry
1 credits    |    Pre-requisite: BCH410 Or BCH415 Or BCH320 Or BCM320
Students learn how to prepare a buffer solution and how to determine its capacity and its pKa. They also learn to distinguish major biochemical molecules (carbohydrates, lipids, proteins) by using specific qualitative tests for this purpose. Glucose in plasma, lipids, triglycerides, proteins in serum, and level of creatinine in urine are evaluated by using spectro­photo­colorimetric techniques.
BIO271Laboratory of General Biology I
1 credits
CHE270Laboratory of General Chemistry
1 credits    |    Pre-requisite: CHM212 Or CHE212 Or CHM210 Or CHE210
The general chemistry laboratory aims to develop different skills for the practical application of theoretical knowledge of general chemistry. Techniques to be learned: preparation and dilution of solutions, experimental verification of the Nernst equation, realization of different types of acid­base and redox titration by volumetric, calorimetric, pH­metric or potentiometric monitoring, and the study of solubility and precipitation reactions and characterization of ions present in a given matrix. The goal of the lab course is to ensure that students are capable of understanding the chemical concepts and to carry out experiments safely and carefully in the laboratory, to obtain data accurately and to manipulate the data correctly.
PHY270Laboratory of General Physics
1 credits
BLG472Laboratory of Molecular Biology
1 credits    |    Pre-requisite: BIO413
This course provides students with the opportunity to practice most of the concepts covered in the course of Molecular Biology (BLG413): genomic and DNA plasmid extractions, PCR amplification, enzyme digestion, SDS­PAGE, Western blot and bacterial transformation.
CHE371Laboratory of Organic Chemistry
1 credits    |    Pre-requisite: (CHM311 Or CHM317) And CHM270
The objective of this practical work is to illustrate by experiment the concepts covered in the course of organic chemistry for students in chemistry and biochemistry and for medical students.
BCM421Metabolic Biochemistry
3 credits    |    Pre-requisite: BCH415 Or BCH410 Or BCH300 Or BCH320 Or BCM320
Understanding all vital processes requires knowledge of the biochemical reactions and their integration in metabolic pathways. This course covers two basic areas of molecular biochemistry which are the production and storage of energy, and the biosynthesis of macromolecules. The course starts with the metabolism of carbohydrates, the main producer of energy in the cell. Several topics are devoted to the study of glycogen metabolism, glycolysis, the Krebs cycle and the pentose phosphate pathway, then lipid metabolism (β oxidation, fatty acid synthesis, cholesterol synthesis), and on protein metabolism (transamination, urea cycle), and then nucleotide metabolism.
BLG413Molecular Biology
3 credits    |    Pre-requisite: BIO411
The course begins with a review of nucleic acids and looks at the methods for their extraction, separation and analysis. Secondly, the course extensively studies the regulation of gene expression and provides an update on the changes to the nucleic acids transcriptionally, post­ transcriptional and translational. Finally, detailed molecular analysis techniques, cloning, PCR, sequencing and development of DNA banks are described.
CHM317Organic Chemistry
3 credits    |    Pre-requisite: CHM212
Organic chemistry is an introduction to the structure, reactivity, and properties of organic compounds. This course is intended to introduce students to the major concepts in organic chemistry and prepare them for the upper level classes in chemistry and biochemistry they will take in the coming semesters and the organic chemistry requirements for medical schools. Topics to include: introduction and review of electronic structure and bonding in organic molecules; nomenclature of organic compounds; structure and properties of alkanes, cycloalkanes, and alkyl halides; stereoisomerism and chirality of organic compounds; and the structure, properties and reactivity of alkynes and alkenes.
BCM320Structural Biochemistry
3 credits    |    Pre-requisite: CHM317 Or CHM311 Or CHE311
This course is based on an understanding of the different biochemical processes taking place in the human body. It enables students to acquire a basic foundation in biochemistry so they are able to competently address all areas related to medical biochemistry. Structural biochemistry defines the structure of the various molecules of living matter such as carbohydrates, lipids, amino acids, proteins, enzymes, nucleotides and vitamins.
Electives - Hybrid
INF304CS for Chemistry, Biochemistry and Biology
3 credits
This course aims to familiarize students of chemistry, biochemistry and biology with the use of advanced software to provide models to illustrate their field of study. Topics include: advanced use of Excel and chemistry applications; tools for drawing molecules; processing molecules in 2D and 3D; introduction to cheminformatics, introduction to bioinformatics and molecular modeling; the structure of proteins (Protein Data Bank and pdb file); demonstration and use of PyMol; and sequence alignment using BioEdit.
CHM426Food chemistry
3 credits
BCH440Fundamentals of biotechnology
3 credits    |    Pre-requisite: BIO413 Or BLG413
This course introduces both the principles and the applications of recombinant DNA technology to animals, plants, and microorganisms. The course describes the use of genetically engineered products to clean the environment and improve human health.
BIO228General Botany
3 credits
BIO336General Immunology
3 credits
BIO411General Microbiology
3 credits    |    Pre-requisite: BIO322 And (BCH410 Or BCH415 Or BCH300 Or BCH320)
This course is designed to give students a comprehensive understanding of bacterial physiology, metabolism, growth conditions, identification, pathogenesis and microbial control methods. It equips students with the tools they will need to understand and address the complex microbial issues related to environmental science, food science, industrial processes and public health. The first part is devoted to the description of bacterial structure (cytoplasm, cytoplasmic membrane, cell wall, glycocalyx, flagella, pili, etc.). The second part studies bacterial metabolism and growth (different trophic types, growth conditions, culture media, etc.). In the third part the main antibiotic families and bacterial genetics are discussed (mechanism of action, spectrum of activity, resistance mechanisms, operons, horizontal genetic transfers, etc.). The fourth part discusses the mechanisms of pathogenicity in bacteria (virulence, toxigenesis, interactions between host and bacteria). The fifth and last part concerns viruses. The basics of virology are explained as well as the different virus families and types, the mechanism of pathogenicity of the virus and the way it affects host cells.
CHM321Inorganic Chemistry
3 credits
BIO473Laboratory of biology & physiology of plant
1 credits
BIO272Laboratory of general biology II
1 credits
BIO471Laboratory of Microbiology
1 credits    |    Pre-requisite: BIO411 Or BIO270
The main purpose of this lab is to teach students all the basics to be able to undertake different types of microbiological analysis (water analysis, food and liquid analysis). It will focus on the basics of good manipulation in a microbiology lab and all the precautions to take to avoid contamination. The students will also learn to identify the types and species of bacteria.
Laboratory of Physics II
1 credits
CHE411Organic Chemistry II
3 credits    |    Pre-requisite: CHM311 Or CHM317
This course covers: types of reactions (substitution, addition, elimination, radical, rearrangement); energetic diagrams (kinetic); mechanisms and reaction intermediates (SN1, SN2, E1, E2, etc.); reactivity and reactions: alkanes, alkenes (Markovnikov rule, Kharash, polymerisation), dienes (Diels­Alder), alkynes; reactivity of halogenated derives (SN2 and Walden inversion, SN1, effect of different parameters, E2 and rule of Saîtzef, E1); benzenic hydrocarbons: electrophilic substitution SE2 (Friedel Crafts alkylation, acylation, effect of the substituent, etc.); aldehydes and ketones (Canizzaro, Wittig, etc.); and organometalics.
Physics II
3 credits
BIO415Systems physiology
3 credits
Specialization - Hybrid
BCH420Biochemical analysis techniques
3 credits    |    Pre-requisite: BIO413 And CHM222 Or BLG413
This course deals with acquiring the laboratory skills required for success in experimental biochemistry and molecular biology. It is particularly suited for students intending a career as a technician or research scientist in the areas of biochemistry, biotechnology, bioengineering, microbiology, or molecular biology. The course content focuses on the detection, purification and identification of biological macromolecules such as proteins and nucleic acids. The material is divided into two equal parts. The first part includes the theory and practice of biological spectroscopy with emphasis on visible, infrared, circular dichroism, optical rotary dispersion, resonance Raman, nuclear magnetic resonance and electron paramagnetic resonance spectroscopy of proteins and nucleic acids. The second part includes the theory and practice of analytical biochemistry with emphasis on diffusion, gel permeation chromatography, ion-exchange chromatography, affinity chromatography, X-ray crystallography, sedimentation velocity ultracentrifugation, sedimentation equilibrium ultracentrifugation, density gradient ultracentrifugation, agarose gel electrophoresis, SDS gel electrophoresis and isoelectric focusing of proteins and nucleic acids.
BCH350Enzyme technology
3 credits    |    Pre-requisite: BCH320
Enzyme technology is one of the key disciplines that a student in Biology, Biochemistry or even Chemistry should master. This course presents the basic concepts of Enzymology. Student also will discover the technological techniques of enzymes in several fields such as scientific research, industry, food, medicine and the environment. Many illustrations have been inserted to clarify or supplement the topics covered. Some exercises and solutions will enable students to improve or to assess their level of knowledge.
BCH445Fundamentals of cell signaling
3 credits    |    Pre-requisite: BCH320
The course is divided into two parts. In the first part, we discuss the structure and dynamics of membranes, the students will receive specialized information concerning lipid and protein composition of the cell membrane, membrane fluidity and cellular traffic. Then, the domain of the translocation of proteins across the membrane will be detailed explaining to the student the destination of a non-cytoplasmic protein (ER, Golgi apparatus, mitochondria, nucleus, and peroxisomes). In the second part, the students will receive a concept on the cell signaling and signal transduction. The different types of membrane receptors and channels of cellular signaling will be described. The various effectors; the coupling mechanisms between receptor and effector, as well as the second messengers produced by these effectors will be detailed.
BCH490Internship
3 credits
An internship is an opportunity offered by an employer to biochemistry students to work at a firm for a fixed, limited period of time. The internship will increase student’s skills and knowledge, improve the understanding of a particular job or industry, and help to gain an insight into the way organizations operate and the challenges they face.
BCM471Laboratory of Enzymology
1 credits    |    Pre-requisite: BCH411 Or BCM411
In part to provide a more authentic experience of actual lab work, experiments are done in groups of two. Each experimental session is started with an explanation, given by the instructor, of the aim, the interest and the steps of the experiment. Prior to each lab period, students need to spend some time reading the Laboratory Manual. This reading provides background information of the procedures to be performed and a facility to answer the prelab questions covered in each session. Students are required to maintain a laboratory notebook used for the recording of laboratory data and calculations, and critically important for writing lab reports. Students are encouraged to participate as much as possible in discussions during the lab work.
BCH430Pharmaceutical biochemistry
3 credits    |    Pre-requisite: BCH421
This course will provide an in-depth look at how novel, pharmacologically active molecules are designed to treat human diseases. Topics will include: Drug discovery; Molecular design; Organic synthesis of drug molecules; Structure-Activity Relationships; Drug interactions with receptors; Pharmacokinetics; Case Histories; Patents; Ethics, and additional examples and applications will be drawn from the published literature. Selected case histories throughout the course will serve to illustrate the concepts.
General Education - English Common Core - English
CHM425Analysis Techniques
3 credits
CHM222Chemistry of Solutions
3 credits
BIO201General biology I
3 credits
This course is an integrated approach to the biology of organisms, covering the chemical and cellular organization of life, the transfer of energy through living systems, as well as heredity, diversity and evolution.
BIO202General biology II
3 credits    |    Pre-requisite: BIO201
This course is designed to provide in-depth knowledge of the evolution, diversity, and function of plants; the evolution, structure, function, and physiology of animals; and the ecology of organisms, populations, communities, and the globe.
BLG322Genetics
3 credits
BIO321Human Anatomy and Physiology
3 credits    |    Pre-requisite: BIO202
This course introduces the basics of human anatomy and physiology, including homeostasis, and the cellular functions of the nervous and endocrine systems. This course will enable the student to establish links between the structure and the function and will present the mechanisms regulating the physiological functions of the human organism.
CHM370Laboratory Of Analytical Chemistry
1 credits
BCH470Laboratory of Biochemistry
1 credits
BIO271Laboratory of General Biology I
1 credits    |    Pre-requisite: BIO201
This laboratory provides a hands-on approach of several biological processes and concepts that have been studied in the accompanying course.
CHE270Laboratory Of General Chemistry
1 credits
PHY270Laboratory of General Physics
1 credits
BLG472Laboratory of Molecular Biology
1 credits
CHE371Laboratory of Organic Chemistry
1 credits
BCH421Metabolic Biochemistry
3 credits
BLG413Molecular Biology
3 credits
CHM317Organic Chemistry
3 credits
BCM320Structural Biochemistry
3 credits
Electives - English Specialization - English
BCH350Enzyme technology
3 credits    |    Pre-requisite: BCH320
Enzyme technology is one of the key disciplines that a student in Biology, Biochemistry or even Chemistry should master. This course presents the basic concepts of Enzymology. Student also will discover the technological techniques of enzymes in several fields such as scientific research, industry, food, medicine and the environment. Many illustrations have been inserted to clarify or supplement the topics covered. Some exercises and solutions will enable students to improve or to assess their level of knowledge.
BCH440Fundamentals of biotechnology
3 credits    |    Pre-requisite: BIO413 Or BLG413
This course introduces both the principles and the applications of recombinant DNA technology to animals, plants, and microorganisms. The course describes the use of genetically engineered products to clean the environment and improve human health.
BCH445Fundamentals of cell signaling
3 credits    |    Pre-requisite: BCH320
The course is divided into two parts. In the first part, we discuss the structure and dynamics of membranes, the students will receive specialized information concerning lipid and protein composition of the cell membrane, membrane fluidity and cellular traffic. Then, the domain of the translocation of proteins across the membrane will be detailed explaining to the student the destination of a non-cytoplasmic protein (ER, Golgi apparatus, mitochondria, nucleus, and peroxisomes). In the second part, the students will receive a concept on the cell signaling and signal transduction. The different types of membrane receptors and channels of cellular signaling will be described. The various effectors; the coupling mechanisms between receptor and effector, as well as the second messengers produced by these effectors will be detailed.
BCH490Internship
3 credits
An internship is an opportunity offered by an employer to biochemistry students to work at a firm for a fixed, limited period of time. The internship will increase student’s skills and knowledge, improve the understanding of a particular job or industry, and help to gain an insight into the way organizations operate and the challenges they face.
CHE471Lab of Chromatography and Spectroscopy
1 credits
BCM471Laboratory of Enzymology
1 credits
BCH430Pharmaceutical biochemistry
3 credits    |    Pre-requisite: BCH421
This course will provide an in-depth look at how novel, pharmacologically active molecules are designed to treat human diseases. Topics will include: Drug discovery; Molecular design; Organic synthesis of drug molecules; Structure-Activity Relationships; Drug interactions with receptors; Pharmacokinetics; Case Histories; Patents; Ethics, and additional examples and applications will be drawn from the published literature. Selected case histories throughout the course will serve to illustrate the concepts.
Holy Spirit University of Kaslik
Tel.: (+961) 9 600 000
Fax : (+961) 9 600 100
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